Research Projects
Our group and the work of our team is dedicated to reduce perinatal brain damage and thus to reduce the neurological sequelae in later life. Prevention of perinatal brain damage is of major importance for public health and obviously for individual well being. The current pathogenetic paradigm of perinatal brain damage in preterm infants has multiple inter-related aspects including infection/inflammation, hypoxia-ischemia, excitotoxicity, and free radicals. It is likely that these mechanisms do not act alone, but in concert.
Current research projects
Experimental research projects
Preventing brain damage in preterms
- Role of sigma 1 receptors in perinatal brain injury
- Anti-oxidative therapies to prevent perinatal brain damage
- Preventing brain damage in newborns by anticonvulsants
Neuroprotection and Neurorepair
- Neuroprotective and neuroregenerative therapeutic strategies using hematopoietic growth factors (G-CSF/SCF and FL) to reduce brain damage
Clinical research projects
Monitoring the developing brain
- Use of amplitude integrated electroencephalography in preterm infants to monitor the developing brain and to predict neurodevelopmental outcome
- Magnetic resonance imaging
- General movements assessment
Follow-up of preterm infants
Children born preterm are at risk for neurodevelopmental delay and disorder. Therefore regular follow-up visits are important not only to provide support for these children and their parents, but also for research purposes and quality control of neonatal intensive care.